Research
Integrative structural biology to function
We use integrative computational and experimental structure–function methods that connect atomic and molecular insights into cellular function and ligand discovery.
Protein NMR spectroscopy · X-ray crystallography · hydrogen/deuterium exchange mass spectrometry· Chemical crosslinking mass spectrometry (XL-MS) · Molecular dynamics (MD) simulations · Biochemical and biophysical assays · Cell-based transcriptional assays · Gene expression · Microscopy · High-throughput screening (HTS) compound discovery